Path ID: DB06480_MESH_D003248_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C406662 | prucalopride | Drug |
| UniProt:Q13639 | 5-hydroxytryptamine receptor 4 | Protein |
| GO:0061526 | acetylcholine secretion | BiologicalProcess |
| GO:0120054 | intestinal motility | BiologicalProcess |
| MESH:D003248 | Constipation | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Prucalopride | POSITIVELY REGULATES | 5-Hydroxytryptamine Receptor 4 |
| 5-Hydroxytryptamine Receptor 4 | POSITIVELY REGULATES | Acetylcholine Secretion |
| Acetylcholine Secretion | POSITIVELY CORRELATED WITH | Intestinal Motility |
| Intestinal Motility | NEGATIVELY CORRELATED WITH | Constipation |
Reference: