Path ID: DB06413_MESH_D009290_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C579652 | Armodafinil | Drug |
| UniProt:Q01959 | Sodium-dependent dopamine transporter | Protein |
| GO:0090494 | Dopamine uptake | BiologicalProcess |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| GO:0042746 | Circadian sleep/wake cycle, wakefulness | BiologicalProcess |
| MESH:D009290 | Narcolepsy | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Armodafinil | DECREASES ACTIVITY OF | Sodium-Dependent Dopamine Transporter |
| Sodium-Dependent Dopamine Transporter | POSITIVELY REGULATES | Dopamine Uptake |
| Dopamine Uptake | DECREASES ABUNDANCE OF | Dopamine |
| Dopamine | POSITIVELY REGULATES | Circadian Sleep/Wake Cycle, Wakefulness |
| Circadian Sleep/Wake Cycle, Wakefulness | NEGATIVELY CORRELATED WITH | Narcolepsy |
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