Path ID: DB06412_MESH_D000741_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D010110 | oxymetholone | Drug |
| UniProt:P10275 | Androgen receptor | Protein |
| GO:0030521 | Androgen receptor signaling pathway | BiologicalProcess |
| GO:0042541 | hemoglobin biosynthetic process | BiologicalProcess |
| GO:0030218 | erythrocyte differentiation | BiologicalProcess |
| MESH:D000741 | Aplastic anemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Oxymetholone | INCREASES ACTIVITY OF | Androgen Receptor |
| Androgen Receptor | POSITIVELY REGULATES | Androgen Receptor Signaling Pathway |
| Androgen Receptor Signaling Pathway | POSITIVELY REGULATES | Hemoglobin Biosynthetic Process |
| Androgen Receptor Signaling Pathway | POSITIVELY REGULATES | Erythrocyte Differentiation |
| Hemoglobin Biosynthetic Process | NEGATIVELY CORRELATED WITH | Aplastic Anemia |
| Erythrocyte Differentiation | NEGATIVELY CORRELATED WITH | Aplastic Anemia |
Reference: