Path ID: DB06401_MESH_D015663_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C447119 | bazedoxifene | Drug |
| UniProt:P03372 | Estrogen receptor | Protein |
| UniProt:Q92731 | Estrogen receptor beta | Protein |
| GO:0001503 | ossification | BiologicalProcess |
| GO:0006874 | cellular calcium ion homeostasis | BiologicalProcess |
| MESH:D015663 | Osteoporosis, Postmenopausal | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bazedoxifene | INCREASES ACTIVITY OF | Estrogen Receptor |
| Bazedoxifene | INCREASES ACTIVITY OF | Estrogen Receptor Beta |
| Estrogen Receptor | POSITIVELY REGULATES | Cellular Calcium Ion Homeostasis |
| Cellular Calcium Ion Homeostasis | POSITIVELY CORRELATED WITH | Ossification |
| Estrogen Receptor Beta | POSITIVELY CORRELATED WITH | Ossification |
| Ossification | NEGATIVELY CORRELATED WITH | Osteoporosis, Postmenopausal |
Reference: