Path ID: DB06372_MESH_D056587_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C531377 | rilonacept | Drug |
| UniProt:P01584 | Interleukin-1 beta | Protein |
| UniProt:P01583 | Interleukin-1 alpha | Protein |
| UniProt:P18510 | Interleukin-1 receptor antagonist protein | Protein |
| GO:0070498 | interleukin-1-mediated signaling pathway | BiologicalProcess |
| GO:0006954 | Inflammation | BiologicalProcess |
| MESH:D056587 | Cryopyrin associated periodic syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Rilonacept | DECREASES ACTIVITY OF | Interleukin-1 Beta |
| Rilonacept | DECREASES ACTIVITY OF | Interleukin-1 Alpha |
| Rilonacept | DECREASES ACTIVITY OF | Interleukin-1 Receptor Antagonist Protein |
| Interleukin-1 Beta | PARTICIPATES IN | Interleukin-1-Mediated Signaling Pathway |
| Interleukin-1 Alpha | PARTICIPATES IN | Interleukin-1-Mediated Signaling Pathway |
| Interleukin-1 Receptor Antagonist Protein | PARTICIPATES IN | Interleukin-1-Mediated Signaling Pathway |
| Interleukin-1-Mediated Signaling Pathway | POSITIVELY REGULATES | Inflammation |
| Inflammation | CAUSES | Cryopyrin Associated Periodic Syndrome |
Reference: