Path ID: DB06287_MESH_D002292_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C401859 | temsirolimus | Drug |
| UniProt:P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | Protein |
| UniProt:P42345 | Serine/threonine-protein kinase mTOR | Protein |
| GO:0008283 | cell population proliferation | BiologicalProcess |
| CL:0001063 | neoplastic cell | Cell |
| MESH:D002292 | Carcinoma, Renal Cell | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Temsirolimus | MOLECULARLY INTERACTS WITH | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1A |
| Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1A | NEGATIVELY REGULATES | Serine/Threonine-Protein Kinase Mtor |
| Serine/Threonine-Protein Kinase Mtor | POSITIVELY REGULATES | Cell Population Proliferation |
| Cell Population Proliferation | OCCURS IN | Neoplastic Cell |
| Neoplastic Cell | CAUSES | Carcinoma, Renal Cell |
Reference: