Path ID: DB06243_MESH_D014353_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000518 | Eflornithine | Drug |
| UniProt:P11926 | Ornithine decarboxylase | Protein |
| GO:0033387 | Putrescine biosynthetic process from ornithine | BiologicalProcess |
| CHEBI:35490 | Trypanothione disulfide | ChemicalSubstance |
| GO:0045454 | Cell redox homeostasis | BiologicalProcess |
| taxonomy:5691 | Trypanosoma brucei | OrganismTaxon |
| MESH:D014353 | African trypanosomiasis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Eflornithine | DECREASES ACTIVITY OF | Ornithine Decarboxylase |
| Ornithine Decarboxylase | POSITIVELY REGULATES | Putrescine Biosynthetic Process From Ornithine |
| Putrescine Biosynthetic Process From Ornithine | POSITIVELY CORRELATED WITH | Trypanothione Disulfide |
| Trypanothione Disulfide | POSITIVELY REGULATES | Cell Redox Homeostasis |
| Cell Redox Homeostasis | IN TAXON | Trypanosoma Brucei |
| Trypanosoma Brucei | CAUSES | African Trypanosomiasis |
Reference: