Path ID: DB06217_MESH_D001281_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C524581 | Vernakalant | Drug |
| GO:0086013 | Membrane repolarization during cardiac muscle cell action potential | BiologicalProcess |
| UniProt:P22460 | Potassium voltage-gated channel subfamily A member 5 | Protein |
| UniProt:Q9UK17 | Potassium voltage-gated channel subfamily D member 3 | Protein |
| UBERON:0000948 | Heart | GrossAnatomicalStructure |
| MESH:D001281 | Atrial fibrillation | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Vernakalant | DECREASES ACTIVITY OF | Potassium Voltage-Gated Channel Subfamily A Member 5 |
| Potassium Voltage-Gated Channel Subfamily A Member 5 | POSITIVELY REGULATES | Membrane Repolarization During Cardiac Muscle Cell Action Potential |
| Vernakalant | DECREASES ACTIVITY OF | Potassium Voltage-Gated Channel Subfamily D Member 3 |
| Potassium Voltage-Gated Channel Subfamily D Member 3 | POSITIVELY REGULATES | Membrane Repolarization During Cardiac Muscle Cell Action Potential |
| Membrane Repolarization During Cardiac Muscle Cell Action Potential | OCCURS IN | Heart |
| Heart | AFFECTED BY | Atrial Fibrillation |
Reference: