Path ID: DB06216_MESH_D012559_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C522667 | Asenapine | Drug |
| UniProt:P28223 | 5-hydroxytryptamine receptor 2A | Protein |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| HP:0000716 | Depressivity | PhenotypicFeature |
| reactome:R-HSA-390651 | Dopamine receptors | Pathway |
| MESH:D012559 | Schizophrenia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Asenapine | DECREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor 2A |
| Asenapine | DECREASES ACTIVITY OF | D(2) Dopamine Receptor |
| 5-Hydroxytryptamine Receptor 2A | POSITIVELY CORRELATED WITH | Depressivity |
| D(2) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine Receptors |
| Depressivity | OCCURS IN | Schizophrenia |
| Dopamine Receptors | CORRELATED WITH | Schizophrenia |
Reference: