Path ID: DB06201_MESH_D065768_1

db06201-mesh-d065768-1

Concepts

Identifier Name Type
MESH:C079703 rufinamide Drug
UniProt:Q15858 Sodium channel protein type 9 subunit alpha Protein
GO:0019228 neuronal action potential BiologicalProcess
GO:0007269 neurotransmitter secretion BiologicalProcess
HP:0032792 Tonic seizure PhenotypicFeature
MESH:D065768 Lennox-Gastaut syndrome Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Rufinamide DECREASES ACTIVITY OF Sodium Channel Protein Type 9 Subunit Alpha
Sodium Channel Protein Type 9 Subunit Alpha POSITIVELY REGULATES Neuronal Action Potential
Neuronal Action Potential POSITIVELY CORRELATED WITH Neurotransmitter Secretion
Neurotransmitter Secretion POSITIVELY CORRELATED WITH Tonic Seizure
Tonic Seizure POSITIVELY CORRELATED WITH Lennox-Gastaut Syndrome

Reference: