Path ID: DB06168_MESH_D056587_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C541220 | Canakinumab | Drug |
| UniProt:P01584 | Interleukin-1 beta | Protein |
| HP:0001945 | Fever | PhenotypicFeature |
| HP:0005059 | Arthralgia/arthritis | PhenotypicFeature |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:D056587 | Cryopyrin associated periodic syndrome | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Canakinumab | DECREASES ACTIVITY OF | Interleukin-1 Beta |
| Interleukin-1 Beta | POSITIVELY REGULATES | Fever |
| Interleukin-1 Beta | POSITIVELY REGULATES | Inflammatory Response |
| Fever | MANIFESTATION OF | Cryopyrin Associated Periodic Syndrome |
| Inflammatory Response | HAS PHENOTYPE | Arthralgia/Arthritis |
| Arthralgia/Arthritis | MANIFESTATION OF | Cryopyrin Associated Periodic Syndrome |
Reference: