Path ID: DB06168_MESH_C536657_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C541220 | Canakinumab | Drug |
| UniProt:P01584 | Interleukin-1 beta | Protein |
| HP:0001945 | Fever | PhenotypicFeature |
| HP:0002829 | Arthralgia | PhenotypicFeature |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:C536657 | TNF receptor-associated periodic fever syndrome (TRAPS) | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Canakinumab | DECREASES ACTIVITY OF | Interleukin-1 Beta |
| Interleukin-1 Beta | POSITIVELY REGULATES | Fever |
| Interleukin-1 Beta | POSITIVELY REGULATES | Inflammatory Response |
| Fever | MANIFESTATION OF | Tnf Receptor-Associated Periodic Fever Syndrome (Traps) |
| Inflammatory Response | HAS PHENOTYPE | Arthralgia |
| Arthralgia | MANIFESTATION OF | Tnf Receptor-Associated Periodic Fever Syndrome (Traps) |
Reference: