Path ID: DB05630_MESH_D007896_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000967 | Antimony Sodium Gluconate | Drug |
| UniProt:Q9NJG8 | DNA topoisomerase I | Protein |
| MESH:D000255 | Adenosine Triphosphate | ChemicalSubstance |
| MESH:D006160 | Guanosine Triphosphate | ChemicalSubstance |
| GO:0009299 | mRNA transcription | BiologicalProcess |
| GO:0006260 | DNA replication | BiologicalProcess |
| taxonomy:5661 | Leishmania donovani | OrganismTaxon |
| MESH:D007896 | Leishmaniasis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Antimony Sodium Gluconate | DECREASES ACTIVITY OF | Dna Topoisomerase I |
| Antimony Sodium Gluconate | DECREASES ABUNDANCE OF | Adenosine Triphosphate |
| Antimony Sodium Gluconate | DECREASES ABUNDANCE OF | Guanosine Triphosphate |
| Dna Topoisomerase I | POSITIVELY REGULATES | Mrna Transcription |
| Dna Topoisomerase I | POSITIVELY REGULATES | Dna Replication |
| Adenosine Triphosphate | OCCURS IN | Leishmania Donovani |
| Guanosine Triphosphate | OCCURS IN | Leishmania Donovani |
| Mrna Transcription | OCCURS IN | Leishmania Donovani |
| Dna Replication | OCCURS IN | Leishmania Donovani |
| Leishmania Donovani | CAUSES | Leishmaniasis |
Reference: