Path ID: DB05197_MESH_D013276_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C035032 | Sofalcone | Drug |
| taxonomy:210 | Helicobacter Pylori | OrganismTaxon |
| UniProt:P15428 | 15-hydroxyprostaglandin dehydrogenase | Protein |
| GO:0009039 | Urease activityS | MolecularActivity |
| CHEBI:15551 | Prostaglandin E2 | ChemicalSubstance |
| MESH:D013276 | Gastric ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sofalcone | DECREASES ACTIVITY OF | 15-Hydroxyprostaglandin Dehydrogenase |
| Sofalcone | DISRUPTS | Helicobacter Pylori |
| Sofalcone | NEGATIVELY REGULATES | Urease Activitys |
| 15-Hydroxyprostaglandin Dehydrogenase | DECREASES ABUNDANCE OF | Prostaglandin E2 |
| Urease Activitys | IN TAXON | Helicobacter Pylori |
| Prostaglandin E2 | TREATS | Gastric Ulcer |
| Helicobacter Pylori | CAUSES | Gastric Ulcer |
Reference: