Path ID: DB04951_MESH_D000080203_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C093844 | Pirfenidone | Drug |
| UniProt:P01375 | Tumor necrosis factor | Protein |
| GO:0006954 | Inflammatory response | BiologicalProcess |
| MESH:D016212 | Transforming Growth Factor beta | ChemicalSubstance |
| GO:0048144 | Fibroblast proliferation | BiologicalProcess |
| MESH:D000080203 | Hamman-Rich syndrome | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Pirfenidone | DECREASES ACTIVITY OF | Tumor Necrosis Factor |
| Pirfenidone | DECREASES ACTIVITY OF | Transforming Growth Factor Beta |
| Pirfenidone | NEGATIVELY REGULATES | Fibroblast Proliferation |
| Tumor Necrosis Factor | POSITIVELY REGULATES | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Hamman-Rich Syndrome |
| Transforming Growth Factor Beta | POSITIVELY CORRELATED WITH | Hamman-Rich Syndrome |
| Fibroblast Proliferation | POSITIVELY CORRELATED WITH | Hamman-Rich Syndrome |
Reference: