Path ID: DB04931_MESH_D046351_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C534526 | Afamelanotide | Drug |
| UniProt:Q01726 | Melanocyte-stimulating hormone receptor | Protein |
| GO:0004977 | Melanocortin receptor activity | MolecularActivity |
| GO:0042438 | Melanin biosynthetic process | BiologicalProcess |
| GO:0009650 | UV protection | BiologicalProcess |
| HP:0000992 | Cutaneous photosensitivity | PhenotypicFeature |
| MESH:D046351 | Erythropoietic protoporphyria | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Afamelanotide | INCREASES ACTIVITY OF | Melanocyte-Stimulating Hormone Receptor |
| Melanocyte-Stimulating Hormone Receptor | PARTICIPATES IN | Melanocortin Receptor Activity |
| Melanocortin Receptor Activity | POSITIVELY REGULATES | Melanin Biosynthetic Process |
| Melanin Biosynthetic Process | POSITIVELY CORRELATED WITH | Uv Protection |
| Uv Protection | NEGATIVELY CORRELATED WITH | Cutaneous Photosensitivity |
| Cutaneous Photosensitivity | MANIFESTATION OF | Erythropoietic Protoporphyria |
Reference: