Path ID: DB04920_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C118563 | clevidipine | Drug |
| MESH:D020746 | Calcium Channels, L-Type | GeneFamily |
| GO:0014829 | vascular associated smooth muscle contraction | BiologicalProcess |
| GO:0006816 | calcium ion transport | BiologicalProcess |
| MESH:D014655 | Vascular Resistance | BiologicalProcess |
| HP:0032263 | Increased blood pressure | PhenotypicFeature |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Clevidipine | NEGATIVELY REGULATES | Calcium Channels, L-Type |
| Calcium Channels, L-Type | POSITIVELY REGULATES | Calcium Ion Transport |
| Calcium Ion Transport | POSITIVELY REGULATES | Vascular Associated Smooth Muscle Contraction |
| Vascular Associated Smooth Muscle Contraction | CONTRIBUTES TO | Vascular Resistance |
| Vascular Resistance | POSITIVELY CORRELATED WITH | Increased Blood Pressure |
| Increased Blood Pressure | MANIFESTATION OF | Hypertensive Disorder |
Reference: