Path ID: DB04865_MESH_D015464_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C001652 | omacetaxine mepesuccinate | Drug |
| UniProt:P39023 | 60S ribosomal protein L3 | Protein |
| GO:0006412 | translation | BiologicalProcess |
| UniProt:A9UF02 | BCR/ABL protein-tyrosine kinase | Protein |
| MESH:D015464 | Chronic myeloid leukemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Omacetaxine Mepesuccinate | DECREASES ACTIVITY OF | 60S Ribosomal Protein L3 |
| 60S Ribosomal Protein L3 | PARTICIPATES IN | Translation |
| Translation | INCREASES ABUNDANCE OF | Bcr/Abl Protein-Tyrosine Kinase |
| Bcr/Abl Protein-Tyrosine Kinase | CAUSES | Chronic Myeloid Leukemia |
Reference: