Path ID: DB04845_MESH_D001943_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C430592 | ixabepilone | Drug |
| InterPro:IPR002453 | Beta-tubulin | GeneFamily |
| GO:1902850 | Microtubule cytoskeleton organization involved in mitosis | BiologicalProcess |
| GO:0140014 | Mitotic nuclear division | BiologicalProcess |
| CL:0001063 | tumor cell | Cell |
| GO:0008283 | Cell population proliferation | BiologicalProcess |
| MESH:D001943 | Carcinoma of breast | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ixabepilone | DECREASES ACTIVITY OF | Beta-Tubulin |
| Beta-Tubulin | PARTICIPATES IN | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Microtubule Cytoskeleton Organization Involved In Mitosis | POSITIVELY CORRELATED WITH | Mitotic Nuclear Division |
| Mitotic Nuclear Division | POSITIVELY CORRELATED WITH | Cell Population Proliferation |
| Cell Population Proliferation | PRECEDES | Tumor Cell |
| Tumor Cell | POSITIVELY CORRELATED WITH | Carcinoma Of Breast |
Reference: