Path ID: DB04830_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002026 | buformin | Drug |
| GO:0001951 | intestinal D-glucose absorption | BiologicalProcess |
| HP:0008189 | Insulin insensitivity | PhenotypicFeature |
| GO:0046323 | glucose import | BiologicalProcess |
| GO:0006094 | gluconeogenesis | BiologicalProcess |
| HP:0003074 | Hyperglycemia | PhenotypicFeature |
| MESH:D003924 | Diabetes mellitus type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Buformin | NEGATIVELY CORRELATED WITH | Intestinal D-Glucose Absorption |
| Buformin | NEGATIVELY CORRELATED WITH | Gluconeogenesis |
| Buformin | NEGATIVELY CORRELATED WITH | Insulin Insensitivity |
| Buformin | INCREASES ACTIVITY OF | Glucose Import |
| Intestinal D-Glucose Absorption | POSITIVELY CORRELATED WITH | Hyperglycemia |
| Gluconeogenesis | POSITIVELY CORRELATED WITH | Hyperglycemia |
| Insulin Insensitivity | POSITIVELY CORRELATED WITH | Hyperglycemia |
| Glucose Import | NEGATIVELY CORRELATED WITH | Hyperglycemia |
| Hyperglycemia | MANIFESTATION OF | Diabetes Mellitus Type 2 |
Comment: Withdrawn from the market in many countries. Never been marketed in the US.
Reference: