Path ID: DB04812_MESH_D001172_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C011677 | benoxaprofen | Drug |
| UniProt:P09917 | Polyunsaturated fatty acid 5-lipoxygenase | Protein |
| GO:0019370 | leukotriene biosynthetic process | BiologicalProcess |
| MESH:D015289 | Leukotrienes | ChemicalSubstance |
| GO:0006954 | inflammatory response | BiologicalProcess |
| HP:0002829 | Arthralgia | PhenotypicFeature |
| MESH:D001172 | Arthritis, Rheumatoid | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Benoxaprofen | DECREASES ACTIVITY OF | Polyunsaturated Fatty Acid 5-Lipoxygenase |
| Polyunsaturated Fatty Acid 5-Lipoxygenase | POSITIVELY REGULATES | Leukotriene Biosynthetic Process |
| Leukotriene Biosynthetic Process | INCREASES ABUNDANCE OF | Leukotrienes |
| Leukotrienes | POSITIVELY REGULATES | Inflammatory Response |
| Inflammatory Response | HAS PHENOTYPE | Arthralgia |
| Arthralgia | MANIFESTATION OF | Arthritis, Rheumatoid |
Reference: