Path ID: DB02701_MESH_D010437_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C061681 | ecabet | Drug |
| CHEBI:16412 | lipopolysaccharide | ChemicalSubstance |
| reactome:R-HSA-166016 | Toll Like Receptor 4 (TLR4) Cascade | Pathway |
| GO:0006954 | inflammatory response | BiologicalProcess |
| UBERON:0001276 | epithelium of stomach | GrossAnatomicalStructure |
| InterPro:IPR017950 | Urease active site | GeneFamily |
| GO:0009039 | urease activity | MolecularActivity |
| taxonomy:210 | Helicobacter pylori | OrganismTaxon |
| MESH:C047874 | gastric mucus glycoproteins | GeneFamily |
| UBERON:0000912 | Mucus | GrossAnatomicalStructure |
| MESH:D005753 | Gastric Mucosa | GrossAnatomicalStructure |
| MESH:D010437 | Peptic ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ecabet | MOLECULARLY INTERACTS WITH | Gastric Mucus Glycoproteins |
| Gastric Mucus Glycoproteins | LOCATED IN | Gastric Mucosa |
| Gastric Mucosa | PRODUCES | Mucus |
| Mucus | NEGATIVELY CORRELATED WITH | Peptic Ulcer |
| Ecabet | DISRUPTS | Lipopolysaccharide |
| Lipopolysaccharide | POSITIVELY REGULATES | Toll Like Receptor 4 (Tlr4) Cascade |
| Toll Like Receptor 4 (Tlr4) Cascade | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | LOCATED IN | Epithelium Of Stomach |
| Epithelium Of Stomach | LOCATION OF | Peptic Ulcer |
| Ecabet | NEGATIVELY REGULATES | Urease Active Site |
| Urease Active Site | POSITIVELY REGULATES | Urease Activity |
| Urease Activity | IN TAXON | Helicobacter Pylori |
| Helicobacter Pylori | CAUSES | Peptic Ulcer |
Reference: