Path ID: DB02701_MESH_D000152_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009536 | nicotinamide | Drug |
| UBERON:0001866 | sebum | GrossAnatomicalStructure |
| HP:0025249 | Comedo | PhenotypicFeature |
| reactome:R-HSA-181438 | Toll Like Receptor 2 (TLR2) Cascade | Pathway |
| taxonomy:1747 | Cutibacterium acnes | OrganismTaxon |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D000152 | Acne vulgaris | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Nicotinamide | DECREASES ACTIVITY OF | Toll Like Receptor 2 (Tlr2) Cascade |
| Toll Like Receptor 2 (Tlr2) Cascade | PART OF | Inflammatory Response |
| Inflammatory Response | CAUSED BY | Cutibacterium Acnes |
| Cutibacterium Acnes | POSITIVELY CORRELATED WITH | Acne Vulgaris |
| Nicotinamide | DECREASES ABUNDANCE OF | Sebum |
| Sebum | POSITIVELY CORRELATED WITH | Comedo |
| Comedo | POSITIVELY CORRELATED WITH | Acne Vulgaris |
Reference: