Path ID: DB01764_MESH_D013290_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C113826 | dalfopristin | Drug |
| UniProt:Q9A1X4 | 50S ribosomal protein L3 (Streptococcus pyogenes) | Protein |
| GO:0005840 | Ribosome | CellularComponent |
| GO:0006412 | Translation | BiologicalProcess |
| GO:0051301 | cell division | BiologicalProcess |
| taxonomy:1314 | Streptococcus pyogenes | OrganismTaxon |
| MESH:D013290 | Streptococcus pyogenes infection | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dalfopristin | NEGATIVELY REGULATES | 50S Ribosomal Protein L3 (Streptococcus Pyogenes) |
| 50S Ribosomal Protein L3 (Streptococcus Pyogenes) | LOCATED IN | Ribosome |
| Ribosome | POSITIVELY REGULATES | Translation |
| Translation | POSITIVELY CORRELATED WITH | Cell Division |
| Cell Division | OCCURS IN | Streptococcus Pyogenes |
| Streptococcus Pyogenes | CAUSES | Streptococcus Pyogenes Infection |
Comment: Dalfopristin is a combination of two antibiotics (Dalfopristin and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium.
Reference: