Path ID: DB01698_MESH_D001206_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D012431 | Rutin | Drug |
| CHEBI:21241 | vitamin C | ChemicalSubstance |
| MESH:D001205 | Ascorbic Acid | ChemicalSubstance |
| MESH:D001206 | Ascorbic acid deficiency | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Rutin | INCREASES ACTIVITY OF | Vitamin C |
| Vitamin C | POSITIVELY CORRELATED WITH | Ascorbic Acid |
| Ascorbic Acid | NEGATIVELY CORRELATED WITH | Ascorbic Acid Deficiency |
Comment: The drug name available in the original file (before curation) was Rutoside. This is one of the synonyms of Rutin, which is the canonical name in DrugBank). Its mechanism of action is not well reported. Some sources have it as an aid to enhance the action of vitamin C (https://www.drugs.com/mtm/rutin.html), whereas others describe rutin (aka vitamin P) acting as a “sparing factor, which slows the oxidation of vitamin C” into dehydroascorbic acid (https://en.wikipedia.org/wiki/Dehydroascorbic_acid).
Reference: