Path ID: DB01624_MESH_D012559_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003006 | zuclopenthixol | Drug |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| UniProt:P21918 | D(1B) dopamine receptor | Protein |
| UniProt:P21728 | D(1A) dopamine receptor | Protein |
| MESH:D004298 | Dopamine | ChemicalSubstance |
| GO:0061527 | Dopamine secretion, neurotransmission | BiologicalProcess |
| MESH:D012559 | Schizophrenia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Zuclopenthixol | DECREASES ACTIVITY OF | D(2) Dopamine Receptor |
| Zuclopenthixol | DECREASES ACTIVITY OF | D(1B) Dopamine Receptor |
| Zuclopenthixol | DECREASES ACTIVITY OF | D(1A) Dopamine Receptor |
| D(2) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(1B) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| D(1A) Dopamine Receptor | POSITIVELY CORRELATED WITH | Dopamine |
| Dopamine | POSITIVELY CORRELATED WITH | Dopamine Secretion, Neurotransmission |
| Dopamine Secretion, Neurotransmission | AFFECTED BY | Schizophrenia |
Reference: