Path ID: DB01603_MESH_D011023_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D008712 | meticillin | Drug |
| UniProt:Q8DR59 | Penicillin-binding protein 1A | Protein |
| UniProt:P0A3M6 | Penicillin-binding protein 2B | Protein |
| GO:0071972 | peptidoglycan L,D-transpeptidase activity | MolecularActivity |
| GO:0008955 | peptidoglycan glycosyltransferase activity | MolecularActivity |
| GO:0018104 | peptidoglycan-protein cross-linking | BiologicalProcess |
| GO:0031504 | peptidoglycan-based cell wall organization | BiologicalProcess |
| taxonomy:1313 | Streptococcus pneumoniae | OrganismTaxon |
| MESH:D011023 | Staphylococcal pneumonia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Meticillin | NEGATIVELY REGULATES | Penicillin-Binding Protein 2B |
| Meticillin | NEGATIVELY REGULATES | Penicillin-Binding Protein 1A |
| Penicillin-Binding Protein 2B | POSITIVELY REGULATES | Peptidoglycan L,D-Transpeptidase Activity |
| Penicillin-Binding Protein 1A | POSITIVELY REGULATES | Peptidoglycan Glycosyltransferase Activity |
| Peptidoglycan L,D-Transpeptidase Activity | POSITIVELY CORRELATED WITH | Peptidoglycan-Protein Cross-Linking |
| Peptidoglycan Glycosyltransferase Activity | POSITIVELY CORRELATED WITH | Peptidoglycan-Protein Cross-Linking |
| Peptidoglycan-Protein Cross-Linking | POSITIVELY CORRELATED WITH | Peptidoglycan-Based Cell Wall Organization |
| Peptidoglycan-Based Cell Wall Organization | IN TAXON | Streptococcus Pneumoniae |
| Streptococcus Pneumoniae | CAUSES | Staphylococcal Pneumonia |
Reference: