Path ID: DB01601_MESH_D015658_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D061466 | lopinavir | Drug |
| UniProt:Q72874 | Protease | Protein |
| GO:0010466 | negative regulation of peptidase activity | BiologicalProcess |
| UniProt:P04591 | Gag polyprotein | Protein |
| GO:0019068 | virion assembly | BiologicalProcess |
| taxonomy:11676 | Human immunodeficiency virus 1 | OrganismTaxon |
| MESH:D015658 | Human immunodeficiency virus infection | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lopinavir | NEGATIVELY REGULATES | Protease |
| Protease | NEGATIVELY CORRELATED WITH | Negative Regulation Of Peptidase Activity |
| Negative Regulation Of Peptidase Activity | DECREASES ACTIVITY OF | Gag Polyprotein |
| Gag Polyprotein | PARTICIPATES IN | Virion Assembly |
| Virion Assembly | IN TAXON | Human Immunodeficiency Virus 1 |
| Human Immunodeficiency Virus 1 | CAUSES | Human Immunodeficiency Virus Infection |
Reference: