Path ID: DB01599_MESH_D006949_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D011341 | probucol | Drug |
| UniProt:O95477 | Phospholipid-transporting ATPase ABCA1 | Protein |
| GO:0008610 | lipid biosynthetic process | BiologicalProcess |
| GO:0140353 | lipid export from cell | BiologicalProcess |
| CHEBI:18059 | lipid | ChemicalSubstance |
| MESH:D006949 | Hyperlipidemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Probucol | NEGATIVELY REGULATES | Lipid Biosynthetic Process |
| Lipid Biosynthetic Process | INCREASES ABUNDANCE OF | Lipid |
| Probucol | DECREASES ACTIVITY OF | Phospholipid-Transporting Atpase Abca1 |
| Phospholipid-Transporting Atpase Abca1 | POSITIVELY REGULATES | Lipid Export From Cell |
| Lipid Export From Cell | INCREASES ABUNDANCE OF | Lipid |
| Lipid | POSITIVELY CORRELATED WITH | Hyperlipidemia |
Reference: