Path ID: DB01591_MESH_D053202_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069464 | solifenacin | Drug |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| UniProt:P08172 | Muscarinic acetylcholine receptor M2 | Protein |
| GO:0014832 | urinary bladder smooth muscle contraction | BiologicalProcess |
| GO:0060073 | micturition | BiologicalProcess |
| MESH:D053202 | Urge incontinence of urine | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Solifenacin | NEGATIVELY REGULATES | Muscarinic Acetylcholine Receptor M3 |
| Solifenacin | NEGATIVELY REGULATES | Muscarinic Acetylcholine Receptor M2 |
| Muscarinic Acetylcholine Receptor M3 | POSITIVELY REGULATES | Urinary Bladder Smooth Muscle Contraction |
| Muscarinic Acetylcholine Receptor M2 | POSITIVELY REGULATES | Urinary Bladder Smooth Muscle Contraction |
| Urinary Bladder Smooth Muscle Contraction | POSITIVELY CORRELATED WITH | Micturition |
| Micturition | POSITIVELY CORRELATED WITH | Urge Incontinence Of Urine |
Reference: