Path ID: DB01501_MESH_D003967_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C100010 | difenoxin | Drug |
| MESH:C028792 | Lyspafen | ChemicalSubstance |
| UniProt:P35372 | Mu-type opioid receptor | Protein |
| GO:0030432 | peristalsis | BiologicalProcess |
| HP:0100770 | Hyperperistalsis | PhenotypicFeature |
| MESH:D003967 | Diarrhea | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Difenoxin | IS METABOLITE OF | Lyspafen |
| Lyspafen | INCREASES ACTIVITY OF | Mu-Type Opioid Receptor |
| Mu-Type Opioid Receptor | NEGATIVELY REGULATES | Peristalsis |
| Peristalsis | POSITIVELY CORRELATED WITH | Hyperperistalsis |
| Hyperperistalsis | CONTRIBUTES TO | Diarrhea |
Reference: