Path ID: DB01436_MESH_D006961_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C008088 | alfacalcidol | Drug |
| UniProt:O15528 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Protein |
| MESH:D002117 | Calcitriol | ChemicalSubstance |
| MESH:D002118 | Calcium | ChemicalSubstance |
| UniProt:P01270 | Parathyroid hormone | Protein |
| MESH:D006961 | Hyperparathyroidism | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Alfacalcidol | MOLECULARLY INTERACTS WITH | 25-Hydroxyvitamin D-1 Alpha Hydroxylase, Mitochondrial |
| 25-Hydroxyvitamin D-1 Alpha Hydroxylase, Mitochondrial | INCREASES ABUNDANCE OF | Calcitriol |
| Calcitriol | POSITIVELY CORRELATED WITH | Calcium |
| Calcium | NEGATIVELY CORRELATED WITH | Parathyroid Hormone |
| Parathyroid Hormone | POSITIVELY CORRELATED WITH | Hyperparathyroidism |
Reference: