Path ID: DB01416_MESH_D013290_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C053267 | cefpodoxime proxetil | Drug |
| InterPro:IPR012338 | Beta-lactamase/transpeptidase-like | GeneFamily |
| InterPro:IPR037532 | Peptidoglycan D,D-transpeptidase FtsI | GeneFamily |
| GO:0009252 | peptidoglycan biosynthetic process | BiologicalProcess |
| GO:0071555 | cell wall organization | BiologicalProcess |
| taxonomy:1301 | Streptococcus | OrganismTaxon |
| MESH:D013290 | Streptococcal Infections | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cefpodoxime Proxetil | DECREASES ACTIVITY OF | Beta-Lactamase/Transpeptidase-Like |
| Cefpodoxime Proxetil | DECREASES ACTIVITY OF | Peptidoglycan D,D-Transpeptidase Ftsi |
| Beta-Lactamase/Transpeptidase-Like | POSITIVELY REGULATES | Peptidoglycan Biosynthetic Process |
| Peptidoglycan D,D-Transpeptidase Ftsi | POSITIVELY REGULATES | Peptidoglycan Biosynthetic Process |
| Peptidoglycan Biosynthetic Process | POSITIVELY CORRELATED WITH | Cell Wall Organization |
| Cell Wall Organization | IN TAXON | Streptococcus |
| Streptococcus | CAUSES | Streptococcal Infections |
Comment: This disease is denoted as Streptococcus pyogenes infection in the original file but it’s named Streptococcal Infections by MESH.
Reference: