Path ID: DB01410_MESH_D001249_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C120481 | ciclesonide | Drug |
| MESH:C494355 | desisobutyryl-ciclesonide | ChemicalSubstance |
| UniProt:P04150 | Glucocorticoid receptor | Protein |
| UniProt:P04083 | lipocortins | Protein |
| UniProt:P47712 | Phospholipase A2 | Protein |
| GO:0006954 | inflammatory response | BiologicalProcess |
| UBERON:0001707 | Nasal cavity | GrossAnatomicalStructure |
| MESH:D001249 | Asthma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ciclesonide | INCREASES ABUNDANCE OF | Desisobutyryl-Ciclesonide |
| Desisobutyryl-Ciclesonide | INCREASES ACTIVITY OF | Glucocorticoid Receptor |
| Glucocorticoid Receptor | INCREASES ABUNDANCE OF | Lipocortins |
| Lipocortins | DECREASES ABUNDANCE OF | Phospholipase A2 |
| Phospholipase A2 | PARTICIPATES IN | Inflammatory Response |
| Inflammatory Response | OCCURS IN | Nasal Cavity |
| Nasal Cavity | CORRELATED WITH | Asthma |
Reference: