Path ID: DB01409_MESH_D011656_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000069447 | tiotropium bromide | Drug |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| GO:1905144 | response to acetylcholine | BiologicalProcess |
| GO:0006939 | smooth muscle contraction | BiologicalProcess |
| UBERON:0002187 | terminal bronchiole | GrossAnatomicalStructure |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D011656 | Pulmonary emphysema | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tiotropium Bromide | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M3 |
| Muscarinic Acetylcholine Receptor M3 | PARTICIPATES IN | Response To Acetylcholine |
| Response To Acetylcholine | POSITIVELY REGULATES | Smooth Muscle Contraction |
| Smooth Muscle Contraction | LOCATED IN | Terminal Bronchiole |
| Terminal Bronchiole | LOCATION OF | Inflammatory Response |
| Inflammatory Response | POSITIVELY CORRELATED WITH | Pulmonary Emphysema |
Reference: