Path ID: DB01400_MESH_D009157_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009388 | Neostigmine | Drug |
| UniProt:P22303 | Acetylcholinesterase | Protein |
| GO:0006581 | Acetylcholine catabolic process | BiologicalProcess |
| GO:0015464 | Acetylcholine receptor activity | MolecularActivity |
| MESH:D000109 | Acetylcholine | ChemicalSubstance |
| MESH:D009157 | Myasthenia gravis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Neostigmine | DECREASES ACTIVITY OF | Acetylcholinesterase |
| Acetylcholinesterase | POSITIVELY REGULATES | Acetylcholine Catabolic Process |
| Acetylcholine Catabolic Process | DECREASES ABUNDANCE OF | Acetylcholine |
| Acetylcholine | INCREASES ACTIVITY OF | Acetylcholine Receptor Activity |
| Acetylcholine Receptor Activity | DISRUPTED BY | Myasthenia Gravis |
Reference: