Path ID: DB01393_MESH_D006949_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D001629 | bezafibrate | Drug |
| UniProt:P37231 | Peroxisome proliferator-activated receptor gamma | Protein |
| UniProt:Q07869 | Peroxisome proliferator-activated receptor alpha | Protein |
| UniProt:Q03181 | Peroxisome proliferator-activated receptor delta | Protein |
| MESH:D008076 | Cholesterol, HDL | ChemicalSubstance |
| MESH:D008078 | Cholesterol, LDL | ChemicalSubstance |
| MESH:D014280 | Triglycerides | ChemicalSubstance |
| HP:0003124 | Hypercholesterolemia | PhenotypicFeature |
| MESH:D006949 | Hyperlipidemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bezafibrate | INCREASES ACTIVITY OF | Peroxisome Proliferator-Activated Receptor Gamma |
| Bezafibrate | INCREASES ACTIVITY OF | Peroxisome Proliferator-Activated Receptor Alpha |
| Bezafibrate | INCREASES ACTIVITY OF | Peroxisome Proliferator-Activated Receptor Delta |
| Peroxisome Proliferator-Activated Receptor Gamma | DECREASES ABUNDANCE OF | Triglycerides |
| Peroxisome Proliferator-Activated Receptor Alpha | DECREASES ABUNDANCE OF | Triglycerides |
| Peroxisome Proliferator-Activated Receptor Delta | DECREASES ABUNDANCE OF | Triglycerides |
| Peroxisome Proliferator-Activated Receptor Gamma | DECREASES ABUNDANCE OF | Cholesterol, Ldl |
| Peroxisome Proliferator-Activated Receptor Alpha | DECREASES ABUNDANCE OF | Cholesterol, Ldl |
| Peroxisome Proliferator-Activated Receptor Delta | DECREASES ABUNDANCE OF | Cholesterol, Ldl |
| Peroxisome Proliferator-Activated Receptor Gamma | INCREASES ABUNDANCE OF | Cholesterol, Hdl |
| Peroxisome Proliferator-Activated Receptor Alpha | INCREASES ABUNDANCE OF | Cholesterol, Hdl |
| Peroxisome Proliferator-Activated Receptor Delta | INCREASES ABUNDANCE OF | Cholesterol, Hdl |
| Cholesterol, Ldl | POSITIVELY CORRELATED WITH | Hypercholesterolemia |
| Cholesterol, Hdl | NEGATIVELY CORRELATED WITH | Hypercholesterolemia |
| Hypercholesterolemia | POSITIVELY CORRELATED WITH | Hyperlipidemia |
| Triglycerides | POSITIVELY CORRELATED WITH | Hyperlipidemia |
Reference: