Path ID: DB01393_MESH_D006937_1

db01393-mesh-d006937-1

Concepts

Identifier Name Type
MESH:D001629 bezafibrate Drug
UniProt:P37231 Peroxisome proliferator-activated receptor gamma Protein
UniProt:Q07869 Peroxisome proliferator-activated receptor alpha Protein
UniProt:Q03181 Peroxisome proliferator-activated receptor delta Protein
MESH:D008076 Cholesterol, HDL ChemicalSubstance
MESH:D008078 Cholesterol, LDL ChemicalSubstance
MESH:D014280 Triglycerides ChemicalSubstance
MESH:D006937 Hypercholesterolemia Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Bezafibrate INCREASES ACTIVITY OF Peroxisome Proliferator-Activated Receptor Gamma
Bezafibrate INCREASES ACTIVITY OF Peroxisome Proliferator-Activated Receptor Alpha
Bezafibrate INCREASES ACTIVITY OF Peroxisome Proliferator-Activated Receptor Delta
Peroxisome Proliferator-Activated Receptor Gamma DECREASES ABUNDANCE OF Triglycerides
Peroxisome Proliferator-Activated Receptor Alpha DECREASES ABUNDANCE OF Triglycerides
Peroxisome Proliferator-Activated Receptor Delta DECREASES ABUNDANCE OF Triglycerides
Peroxisome Proliferator-Activated Receptor Gamma DECREASES ABUNDANCE OF Cholesterol, Ldl
Peroxisome Proliferator-Activated Receptor Alpha DECREASES ABUNDANCE OF Cholesterol, Ldl
Peroxisome Proliferator-Activated Receptor Delta DECREASES ABUNDANCE OF Cholesterol, Ldl
Peroxisome Proliferator-Activated Receptor Gamma INCREASES ABUNDANCE OF Cholesterol, Hdl
Peroxisome Proliferator-Activated Receptor Alpha INCREASES ABUNDANCE OF Cholesterol, Hdl
Peroxisome Proliferator-Activated Receptor Delta INCREASES ABUNDANCE OF Cholesterol, Hdl
Cholesterol, Hdl NEGATIVELY CORRELATED WITH Hypercholesterolemia
Cholesterol, Ldl POSITIVELY CORRELATED WITH Hypercholesterolemia
Triglycerides POSITIVELY CORRELATED WITH Hypercholesterolemia

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