Path ID: DB01356_MESH_D010003_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D016651 | Lithium carbonate | Drug |
| UniProt:P29218 | Inositol monophosphatase 1 | Protein |
| GO:0046855 | Inositol phosphate dephosphorylation | BiologicalProcess |
| MESH:D007294 | Inositol | BiologicalProcess |
| GO:0043647 | Inositol phosphate metabolic process | BiologicalProcess |
| GO:0014047 | Glutamate secretion | BiologicalProcess |
| GO:0019233 | Sensory perception of pain | BiologicalProcess |
| GO:0004972 | NMDA glutamate receptor activity | MolecularActivity |
| MESH:D018698 | Glutamic Acid | ChemicalSubstance |
| GO:0061535 | Glutamate secretion, neurotransmission | BiologicalProcess |
| MESH:D010003 | Osteoarthritis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lithium Carbonate | DECREASES ACTIVITY OF | Inositol Monophosphatase 1 |
| Inositol Monophosphatase 1 | POSITIVELY REGULATES | Inositol Phosphate Dephosphorylation |
| Inositol Phosphate Dephosphorylation | INCREASES ABUNDANCE OF | Inositol |
| Inositol | POSITIVELY REGULATES | Inositol Phosphate Metabolic Process |
| Inositol Phosphate Metabolic Process | POSITIVELY REGULATES | Glutamate Secretion |
| Glutamate Secretion | POSITIVELY CORRELATED WITH | Sensory Perception Of Pain |
| Lithium Carbonate | NEGATIVELY REGULATES | Nmda Glutamate Receptor Activity |
| Nmda Glutamate Receptor Activity | POSITIVELY CORRELATED WITH | Glutamic Acid |
| Glutamic Acid | POSITIVELY CORRELATED WITH | Glutamate Secretion, Neurotransmission |
| Glutamate Secretion, Neurotransmission | POSITIVELY CORRELATED WITH | Sensory Perception Of Pain |
| Sensory Perception Of Pain | POSITIVELY CORRELATED WITH | Osteoarthritis |
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