Path ID: DB01332_MESH_D011023_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015296 | ceftizoxime | Drug |
| InterPro:IPR001460 | Penicillin-binding protein, transpeptidase | GeneFamily |
| GO:0009252 | peptidoglycan biosynthetic process | BiologicalProcess |
| GO:0009273 | peptidoglycan-based cell wall biogenesis | BiologicalProcess |
| taxonomy:1280 | Staphylococcus aureus | OrganismTaxon |
| MESH:D011023 | Pneumonia, Staphylococcal | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ceftizoxime | DECREASES ACTIVITY OF | Penicillin-Binding Protein, Transpeptidase |
| Penicillin-Binding Protein, Transpeptidase | PARTICIPATES IN | Peptidoglycan Biosynthetic Process |
| Peptidoglycan Biosynthetic Process | POSITIVELY REGULATES | Peptidoglycan-Based Cell Wall Biogenesis |
| Peptidoglycan-Based Cell Wall Biogenesis | OCCURS IN | Staphylococcus Aureus |
| Staphylococcus Aureus | CAUSES | Pneumonia, Staphylococcal |
Comment: Ceftizoxime is a semisynthetic, third-generation cephalosporin antibiotic which can be administered intravenously or by suppository for the treatment of various bacterial infections.
Reference: