Path ID: DB01327_MESH_D011018_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002437 | Cefazolin | Drug |
| InterPro:IPR001460 | Penicillin-binding protein, transpeptidase | GeneFamily |
| GO:0018104 | Cross-linking of the peptidoglycan | BiologicalProcess |
| GO:0009273 | Peptidoglycan-based cell wall biogenesis | BiologicalProcess |
| GO:0005618 | Cell wall | CellularComponent |
| taxonomy:1313 | Streptococcus pneumoniae | OrganismTaxon |
| MESH:D011018 | Pneumonia due to Streptococcus | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cefazolin | DECREASES ACTIVITY OF | Penicillin-Binding Protein, Transpeptidase |
| Penicillin-Binding Protein, Transpeptidase | POSITIVELY REGULATES | Cross-Linking Of The Peptidoglycan |
| Cross-Linking Of The Peptidoglycan | POSITIVELY REGULATES | Peptidoglycan-Based Cell Wall Biogenesis |
| Peptidoglycan-Based Cell Wall Biogenesis | HAS OUTPUT | Cell Wall |
| Cell Wall | OCCURS IN | Streptococcus Pneumoniae |
| Streptococcus Pneumoniae | CAUSES | Pneumonia Due To Streptococcus |
Reference: