Path ID: DB01291_MESH_D008171_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C009118 | Pirbuterol | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| UniProt:B7Z2C7 | Adenylate cyclase | Protein |
| CHEBI:17489 | 3’,5’-cyclic AMP | ChemicalSubstance |
| GO:0044557 | Relaxation of smooth muscle | BiologicalProcess |
| UBERON:0002187 | Terminal bronchiole | GrossAnatomicalStructure |
| MESH:D008171 | Disorder of lung | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Pirbuterol | POSITIVELY REGULATES | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | POSITIVELY REGULATES | Adenylate Cyclase |
| Adenylate Cyclase | INCREASES ABUNDANCE OF | 3’,5’-Cyclic Amp |
| 3’,5’-Cyclic Amp | POSITIVELY CORRELATED WITH | Relaxation Of Smooth Muscle |
| Relaxation Of Smooth Muscle | LOCATED IN | Terminal Bronchiole |
| Terminal Bronchiole | AFFECTED BY | Disorder Of Lung |
Reference: