Path ID: DB01281_MESH_D001172_1

db01281-mesh-d001172-1

Concepts

Identifier Name Type
MESH:D000069594 Abatacept Drug
UniProt:P33681 T-lymphocyte activation antigen CD80 Protein
UniProt:P42081 T-lymphocyte activation antigen CD86 Protein
UniProt:P10747 T-cell-specific surface glycoprotein CD28 Protein
GO:0032743 Positive regulation of interleukin-2 production BiologicalProcess
GO:0042102 Positive regulation of T cell proliferation BiologicalProcess
GO:0042110 T cell activation BiologicalProcess
MESH:D001172 Rheumatoid arthritis Drug

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Abatacept DECREASES ACTIVITY OF T-Lymphocyte Activation Antigen Cd80
Abatacept DECREASES ACTIVITY OF T-Lymphocyte Activation Antigen Cd86
T-Lymphocyte Activation Antigen Cd80 INCREASES ACTIVITY OF T-Cell-Specific Surface Glycoprotein Cd28
T-Lymphocyte Activation Antigen Cd86 INCREASES ACTIVITY OF T-Cell-Specific Surface Glycoprotein Cd28
T-Cell-Specific Surface Glycoprotein Cd28 PARTICIPATES IN Positive Regulation Of Interleukin-2 Production
T-Cell-Specific Surface Glycoprotein Cd28 PARTICIPATES IN Positive Regulation Of T Cell Proliferation
T-Cell-Specific Surface Glycoprotein Cd28 PARTICIPATES IN T Cell Activation
Positive Regulation Of Interleukin-2 Production POSITIVELY CORRELATED WITH Rheumatoid Arthritis
T Cell Activation POSITIVELY CORRELATED WITH Rheumatoid Arthritis
Positive Regulation Of T Cell Proliferation POSITIVELY CORRELATED WITH Rheumatoid Arthritis

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