Path ID: DB01274_MESH_D029424_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| DB:DB01274 | Arformoterol | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| InterPro:IPR030672 | Adenylate cyclase | GeneFamily |
| MESH:D000242 | Cyclic AMP | ChemicalSubstance |
| GO:0006939 | Smooth muscle contraction | BiologicalProcess |
| UBERON:0002185 | Bronchus | GrossAnatomicalStructure |
| MESH:D029424 | Chronic obstructive lung disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Arformoterol | INCREASES ACTIVITY OF | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | INCREASES ACTIVITY OF | Adenylate Cyclase |
| Adenylate Cyclase | INCREASES ABUNDANCE OF | Cyclic Amp |
| Cyclic Amp | NEGATIVELY CORRELATED WITH | Smooth Muscle Contraction |
| Smooth Muscle Contraction | OCCURS IN | Bronchus |
| Bronchus | AFFECTED BY | Chronic Obstructive Lung Disease |
Reference: