Path ID: DB01267_MESH_D012559_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068882 | Paliperidone Palmitate | Drug |
| MESH:D018967 | Risperidone | ChemicalSubstance |
| UniProt:P28223 | 5-hydroxytryptamine receptor 2A | Protein |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| GO:1904014 | response to serotonin | BiologicalProcess |
| GO:1903350 | response to dopamine | BiologicalProcess |
| HP:0000738 | Hallucinations | PhenotypicFeature |
| MESH:D012559 | Schizophrenia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Paliperidone Palmitate | IS METABOLITE OF | Risperidone |
| Risperidone | DECREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor 2A |
| Risperidone | DECREASES ACTIVITY OF | D(2) Dopamine Receptor |
| 5-Hydroxytryptamine Receptor 2A | PARTICIPATES IN | Response To Serotonin |
| D(2) Dopamine Receptor | PARTICIPATES IN | Response To Dopamine |
| Response To Dopamine | CORRELATED WITH | Hallucinations |
| Response To Serotonin | CORRELATED WITH | Schizophrenia |
| Hallucinations | MANIFESTATION OF | Schizophrenia |
Reference: