Path ID: DB01263_MESH_D003047_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C101425 | Posaconazole | Drug |
| UniProt:A0A6C1LUF2 | Lanosterol 14-alpha demethylase (Coccidioides immitis) | Protein |
| GO:0006696 | Ergosterol biosynthetic process | BiologicalProcess |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| taxonomy:5501 | Coccidioides immitis | OrganismTaxon |
| MESH:D003047 | Coccidioidomycosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Posaconazole | DECREASES ACTIVITY OF | Lanosterol 14-Alpha Demethylase (Coccidioides Immitis) |
| Lanosterol 14-Alpha Demethylase (Coccidioides Immitis) | POSITIVELY REGULATES | Ergosterol Biosynthetic Process |
| Ergosterol Biosynthetic Process | PRECEDES | Cell Wall Biogenesis |
| Cell Wall Biogenesis | OCCURS IN | Coccidioides Immitis |
| Coccidioides Immitis | CAUSES | Coccidioidomycosis |
Reference: