Path ID: DB01263_MESH_D001228_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C101425 | Posaconazole | Drug |
| UniProt:B8N2C8 | Lanosterol 14-alpha demethylase (Aspergillus flavus) | Protein |
| GO:0006696 | Ergosterol biosynthetic process | BiologicalProcess |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| taxonomy:5052 | Aspergillus | OrganismTaxon |
| MESH:D001228 | Aspergillosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Posaconazole | DECREASES ACTIVITY OF | Lanosterol 14-Alpha Demethylase (Aspergillus Flavus) |
| Lanosterol 14-Alpha Demethylase (Aspergillus Flavus) | POSITIVELY REGULATES | Ergosterol Biosynthetic Process |
| Ergosterol Biosynthetic Process | PRECEDES | Cell Wall Biogenesis |
| Cell Wall Biogenesis | OCCURS IN | Aspergillus |
| Aspergillus | CAUSES | Aspergillosis |
Reference: