Path ID: DB01257_MESH_D006457_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C481642 | Eculizumab | Drug |
| UniProt:P01031 | Complement C5 | Protein |
| GO:0006956 | Complement activation | BiologicalProcess |
| HP:0001878 | Hemolytic anemia | PhenotypicFeature |
| MESH:D006457 | Paroxysmal nocturnal hemoglobinuria | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Eculizumab | DECREASES ACTIVITY OF | Complement C5 |
| Complement C5 | PARTICIPATES IN | Complement Activation |
| Complement Activation | CONTRIBUTES TO | Hemolytic Anemia |
| Hemolytic Anemia | MANIFESTATION OF | Paroxysmal Nocturnal Hemoglobinuria |
Reference: