Path ID: DB01251_MESH_D003924_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C010969 | gliquidone | Drug |
| UniProt:Q15842 | ATP-sensitive inward rectifier potassium channel 8 | Protein |
| GO:0086009 | membrane repolarization | BiologicalProcess |
| GO:0070509 | calcium ion import | BiologicalProcess |
| GO:0030073 | insulin secretion | BiologicalProcess |
| MESH:D003924 | Diabetes mellitus type 2 | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Gliquidone | NEGATIVELY REGULATES | Atp-Sensitive Inward Rectifier Potassium Channel 8 |
| Atp-Sensitive Inward Rectifier Potassium Channel 8 | PARTICIPATES IN | Membrane Repolarization |
| Membrane Repolarization | NEGATIVELY REGULATES | Calcium Ion Import |
| Calcium Ion Import | POSITIVELY REGULATES | Insulin Secretion |
| Insulin Secretion | NEGATIVELY CORRELATED WITH | Diabetes Mellitus Type 2 |
Reference: