Path ID: DB01244_MESH_D000787_8
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015764 | Bepridil | Drug |
| UniProt:P54750 | Calcium/calmodulin-dependent 3’,5’-cyclic nucleotide phosphodiesterase 1A | Protein |
| UniProt:Q01064 | Calcium/calmodulin-dependent 3’,5’-cyclic nucleotide phosphodiesterase 1B | Protein |
| MESH:D002147 | Calmodulin | Protein |
| GO:0060048 | cardiac muscle contraction | BiologicalProcess |
| MESH:D017202 | Myocardial Ischemia | PhenotypicFeature |
| MESH:D000787 | Angina pectoris | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bepridil | NEGATIVELY REGULATES | Calcium/Calmodulin-Dependent 3’,5’-Cyclic Nucleotide Phosphodiesterase 1B |
| Bepridil | NEGATIVELY REGULATES | Calcium/Calmodulin-Dependent 3’,5’-Cyclic Nucleotide Phosphodiesterase 1A |
| Calcium/Calmodulin-Dependent 3’,5’-Cyclic Nucleotide Phosphodiesterase 1B | MOLECULARLY INTERACTS WITH | Calmodulin |
| Calcium/Calmodulin-Dependent 3’,5’-Cyclic Nucleotide Phosphodiesterase 1A | MOLECULARLY INTERACTS WITH | Calmodulin |
| Calmodulin | POSITIVELY CORRELATED WITH | Cardiac Muscle Contraction |
| Cardiac Muscle Contraction | NEGATIVELY CORRELATED WITH | Myocardial Ischemia |
| Myocardial Ischemia | POSITIVELY CORRELATED WITH | Angina Pectoris |
Reference: